Tiamulin 55297-96-6

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Last update: 2016-09-18 11:42
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Product details
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Pharmaceuticals and Biochemicals/Antibiotic and antimicrobial agents

Tiamulin
CAS NO : 55297-96-6
EC NO : 259-581-6
MF : C32H51NO8S
MW : 609.8142
Specification : EP/USP/Feed Grade
Packing : 25kg drum
Product description :

TIAMULIN

COMMON NAME: Tiamulin Hydrogen Fumarate

 

MOLECULAR FORMULAR: C28H47NO4S·C4H4O4

 

MOLECULAR WEIGHT: 609.82

 

SPECIFICATION

Items

 

Technical Specifications

Specifications

Appearance

White crystal powder

Identification

IR-spectrum/HPLC retention times

 

pH

From 3.1 to 4.1

Loss on drying

Not more than 0.5%

Heavy metals (ppm)

Not more than 10

Fumarate assay

18.6-19.4%

Assay (HPLC)

98.0-102.0%

 

INDICATION

Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E. coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to tiamulin.

Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to 70S ribosomes.

Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; and swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.

 

CAUTION

Dont use together with polyether ionophores such as Monesin, Salinomycin etc.

Dont touch with eyes and skin.

 

STORAGE

Keep in dry ,cool places; Seal the bag after use.

 

PACKAGE

25 Kg drum

Uses : Antibiotic for Animal Use
Synonyms : Tiamuline Hydrogen Fumarate;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;DENAGARD;,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles;14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate;14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato;81723hfu;dynamutilin;sandoz81723hfu;Tiamulin Fumarate;(4R,5S,6S,8R,9aS,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);(3aS,4R,5S,6S,8R,9R,9aR)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);
Molecular Structure : Tiamulin 55297-96-6
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